Client Success Stories
Discover how our innovative research solutions have helped clients overcome challenges and achieve breakthrough results
Wound Healing
CHALLENGE:
To select the best, simplest, and most cost-effective model for wound healing while ensuring comprehensive data for product launch within a single short-term experiment.
SOLUTION:
Cology Biosciences customized an optimized wound healing study design to maximize data collection in a single short-term experiment.
Vitiligo Model
CHALLENGE:
To develop a mouse model for vitiligo that is more human-relevant, less mortal, cost-effective, and capable of accelerating drug screening and IP generation.
SOLUTION:
Cology Biosciences customized an innovative vitiligo mouse model with superior translational relevance and reduced mortality.
Pharmacokinetics
CHALLENGE:
To conduct pharmacokinetic (PK) studies for finished dosage forms—sublingual films, sublingual tablets, nasal sprays, and eye drops—to support clients' 505(b)(2) applications, patent filings, and clinical trial entry.
SOLUTION:
Cology Biosciences successfully designed and executed PK studies tailored to each dosage form.
Dry Eye Syndrome
CHALLENGE:
To develop and optimize a nasal spray for inducing natural tears in dry eye syndrome, enabling the client to identify a lead formulation with robust data.
SOLUTION:
Cology Biosciences designed a customized study to screen and quantify the efficacy of nasal spray formulations.
Hepatotoxicity Model
CHALLENGE:
To evaluate the hepatoprotective potential of stem cell therapy by developing a human-relevant hepatotoxicity model and providing comprehensive preclinical data for regulatory and scientific validation.
SOLUTION:
Cology Biosciences designed a fully customized hepatotoxicity animal model aligned with human intended use.
Metabolic Disorders
CHALLENGE:
To evaluate the lipid-lowering potential of a test item and generate meaningful preclinical data for further development.
SOLUTION:
Cology Biosciences designed a highly strategic and insightful study that uncovered unexpected therapeutic potential.
Renal Drug Delivery
CHALLENGE:
To develop a targeted drug delivery approach for mice renal cells, requiring precise and complex surgical techniques to optimize efficacy.
SOLUTION:
Cology Biosciences successfully established and optimized multiple advanced mouse surgical techniques for targeted renal delivery.
Microbiome Analysis
CHALLENGE:
To evaluate the gut microbiota-modulating potential of a test item through a long-term preclinical study with comprehensive microbiome analysis.
SOLUTION:
Cology Biosciences designed and executed a 14-week study with meticulous data collection and analysis.
Infectious Disease
CHALLENGE:
To develop a cost-effective in vivo mouse model for dengue virus that allows screening of potential drug candidates despite budget constraints.
SOLUTION:
Cology Biosciences successfully established a dengue virus model in normal mice, enabling efficient drug screening.
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